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Nouvelles protéines chimiques et leurs procédés d'utilisation
专利权人:
THE TRUSTEES OF THE UNIVERSITY OF PENNSYLVANIA
发明人:
申请号:
EP07006581.8
公开号:
EP1908780B1
申请日:
2001.01.03
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
Novel chimeric proteins are disclosed. The proteins comprise at least two portions. The first portion binds to a first cell and decreases the cell's ability to send a trans signal to a second cell; the second portion send its own trans signal to the second cell. Methods for making and using these proteins in the treatment of cancer, viral infections, autoimmune and alloimmune diseases are also disclosed, as are pharmaceutical formulations comprising the novel chimeric proteins and genes. Either the proteins themselves or a genetic sequence encoding the protein can be administered. Other methods are also disclosed in which two molecular components result in decrement of a first trans signal from a first cell and the conferring of a second trans signal to a second cell.
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中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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