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Bioresorbable nitric oxide agonist prodrug scaffolds for vascular stents
专利权人:
Wayne H Kaesemeyer
发明人:
Wayne H Kaesemeyer
申请号:
US13426948
公开号:
US08936635B2
申请日:
2012.03.22
申请国别(地区):
US
年份:
2015
代理人:
摘要:
The present invention relates to a bioresorbable scaffold for a vascular stent comprising a nitric oxide agonist and a polymer comprising a lactide, a glycolide and a lactone. The nitric oxide agonist is a statin or a HMG CoA reductase inhibitor. The nitric oxide agonist may be coated on the polymer, incorporated within the polymer or chemically bonded to the polymer. The invention also relates to a method for treating atherothrombosclerotic occlusive disease of an artery comprising implanting into the artery a stent with a bioresorbable scaffold comprising a nitric oxide agonist and a polymer comprising a lactide, a glycolide and a lactone, wherein the nitric oxide agonist is exuded from or released from the bioresorbable scaffold.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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