MIRAGLIA NICCOLÒ,BIANCHI, DAVIDE,VALOTI ,ERMANNO,TRENTIN, ANTONELLA,TRILLI ,ANTONIO,BUSIELLO, IMMACOLATA,AGOSTINETTO, MARCO,BAZZA ,PAOLA,VALETTI MARCO
申请号：
IN9832DEN2014
公开号：
IN9832DEN2014A
申请日:
2014.11.20
申请国别(地区):
IN
年份:
2015
代理人:
摘要：
Disclosed is a low -molecular- weight (1000- 5000 daltons) chondroitin sulphate (CS) produced by chemical sulphation and subsequent depolymerisation of a non -sulphated chondroitin backbone obtained with biotechnology techniques. The CS described is substantially mono sulphated , mainly at the 6- position, with very little sulphation at the 4 -position , and with a mono/disulphated disaccharide ratio and charge density similar to those of natural CS. Said biotechnological chondroitin 6- sulphate (C6S) is useful in the treatment and prevention of osteoarthritis and in acute and chronic inflammatory processes.
