The object of the present invention is to suppress the canceration of cells and the progression of cancer, that is, the onset of cancer, or to induce cell death of cancer cells. The present invention provides a composition for suppressing the proliferation of cancer cells, an anti-cancer composition, a composition for suppressing canceration of normal cells, and an inhibitory effect of cancer, comprising at least one of curcuminol A and curcuminol B as active ingredients. A composition and a composition for inducing cancer cell death.本發明之課題在於抑制細胞之癌化及癌症之惡化發展即癌症之發病、或誘導癌細胞之細胞死亡。本發明提供一種含有薑黃酮醇A及薑黃酮醇B之至少1種作為有效成分之癌細胞之增殖抑制用組合物、抗癌用組合物、正常細胞之癌化抑制用組合物、癌症發病抑制用組合物、及癌細胞死亡誘導用組合物。