N - (3 - (3 - [[{{2 - Chloro - 5 - (methoxy) phenyl] amino} - 2 quinoxalin - il) amino] sulfonyl] phenyl) - 2 - metilalaninamida as inhibitor of phosphatidylinositol 3 - kinase for the treatment of lymphoproliferative Neoplasms

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专利权人:

EXELIXIS; INC.

发明人:

DECILLIS, ARTHUR,LAGER, JOANNE

申请号：

PE0006322014

公开号：

PE17942014A1

申请日:

2012.11.01

申请国别(地区):

PE

年份:

2014

代理人:

摘要：

It relates to a method for the treatment of a lymphoproliferative disease such as Chronic Lymphocytic Leukemia, Hodgkins Lymphoma, follicular Lymphoma, among others.That includes the daily Administration of a Single Dose of 200mg in Tablet form to 600mg Compound N - (3 - (3 - [[{{2 - Chloro - 5 - (methoxy) phenyl] amino} quinoxalin thiocyanatoacetate) amino] sulfonyl] phenyl) - 2 - metIlalaninamida or a pharmaceutically acceptable Salt thereof. This Compound is an inhibitor of phosphatidylinositol 3-kinaseSE REFIERE A UN METODO PARA EL TRATAMIENTO DE UNA NEOPLASIA LINFOPROLIFERATIVA TAL COMO LEUCEMIA LINFOCITICA CRONICA, LINFOMA DE HODGKIN, LINFOMA FOLICULAR, ENTRE OTROS, QUE COMPRENDE LA ADMINISTRACION DIARIA DE UNA DOSIS UNICA EN FORMA DE COMPRIMIDO DE 200MG A 600MG DEL COMPUESTO N-(3-{[(3-{[2-CLORO-5-(METOXI)FENIL]AMINO}QUINOXALIN-2-ILO)AMINO]SULFONILO}FENIL)-2-METILALANINAMIDA O UNA SAL FARMACEUTICAMENTE ACEPTABLE DEL MISMO. DICHO COMPUESTO ES UN INHIBIDOR DE LA FOSFATIDILINOSITOL 3-QUINASA

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