GIRISH DAGINAKATTE,KAVITHA NELLORE,SUSANTA SAMAJDAR,VENKATESHWAR RAO GUMMADI,WESLEY ROY BALASUBRAMANIAN
申请号:
BR112019018991
公开号:
BR112019018991A2
申请日:
2018.03.30
申请国别(地区):
BR
年份:
2020
代理人:
摘要:
the present invention relates to methods of treating hematological disorders, such as acute myeloid leukemia, using substituted heterocyclic compounds and pharmaceutically acceptable salts thereof. the compounds inhibit irak4 and flt-3 kinases.a presente invenção refere-se a métodos de tratamento de distúrbios hematológicos, tais como leucemia mieloide aguda, utilizando compostos heterocíclicos substituídos e sais farmaceuticamente aceitáveis dos mesmos. os compostos inibem as quinases irak4 e flt-3.