A pneumatic pressure pulse cleaning machine includes a container body, which has a rear side to which a container cover is rotatably mounted and also has an interior space in which a pipe assembly that includes pipes connected together to form a grating configuration is received. The pipe assembly has a plurality of through holes formed therein and facing upwards. A support board is received in the interior space and arranged above the pipe assembly so that an article disposition zone is provided in the container body above the support board. The pipe assembly includes a joint, which is connectable with a tube for connection with a pneumatic pressure source. Articles to be washed are positioned on the support board. The pneumatic pressure source is activated to generate pneumatic pressure pulses that are ejected through the through holes to impinge and thus clean the articles.