PURPOSE: A composition for preventing or treating hypertension is provided to have the potential to inhibit excessive vasoconstriction by inhibition of EGFR tyrosine kinase and PLC gamma and to be a medicine for hypertension better than the current calcium channel blocker on the market. CONSTITUTION: A composition for preventing or treating hypertension contains epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor AG 1478, SP600125, or genistein as an active ingredient. An identification method of medicine for preventing or treating hypertension, or a vasodilator compound comprises: a step of reacting the EGFR tyrosine kinase with at least one test compound； and a step of measuring the activity reduction of the EGFR tyrosine kinase and identifying the test compound as the medicine for preventing or treating hypertension, or a vasodilator compound comprises if the activity is decreased.본 발명은 포스포리파제 C감마 또는 표피성장인자 수용체 저해제를 유효성분으로 포함하는 고혈압 치료 또는 예방용 조성물 또는 혈관 확장제 조성물에 관한 것이다.
