PHARMACEUTICAL COMPOSITION COMPRISING GEMFIBROZIL AND CYP2C8 AND/OR OATP SUBSTRATE DRUG SUCH AS REPAGLINIDE

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专利权人:

Pertti Neuvonen

发明人:

Pertti Neuvonen,Mikko Niemi,Janne Backman

申请号：

US13637519

公开号：

US20130040991A1

申请日:

2011.03.29

申请国别(地区):

US

年份:

2013

代理人:

摘要：

The invention provides gemfibrozil for use in adjusting the effect of a CYP2C8 and/or OATP substrate drug, wherein gemfibrozil is administered in an amount of less than 1200 mg/day. The invention also provided a pharmaceutical composition comprising gemfibrozil providing a significant improvement to the plasma profiles of a CYP2C8 and/or OATP substrate drug in a mammal.

来源网站：

中国工程科技知识中心

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http://www.ckcest.cn/home/