IBET - INSTITUTO DE BIOLOGIA EXPERIMENTAL E TECNOLOGICA
发明人:
Helder Joao FERREIRA VILA REAL,Ana Luisa FERREIRA SIMPLICIO,Olga IRANZO CASANOVA,Christopher David MAYCOCK
申请号：
US15099860
公开号：
US20170296618A1
申请日:
2016.04.15
申请国别(地区):
US
年份:
2017
代理人:
摘要：
The present application presents novel peptidomimetic substituted hydroxyethylene compounds, which are inhibitors of beta amyloid cleavage enzyme, capable to permeate the brain and to achieve therapeutic concentrations in the target organ, the brain. These compounds are incorporated in pharmaceutical compositions and applied in the treatment or prophylaxis of neurological disorders or conditions and also other disorders or conditions including Down's syndrome and diabetes.
