The invention features isolated cytochrome P450 polypeptides and nucleic acidmolecules, as well as expression vectors and transgenic plants containingthese molecules. In addition, the invention features uses of such molecules inmethods of increasing the level of resistance against a disease caused by aplant pathogen in a transgenic plant, in methods for producing alteredcompounds, for example, hydroxylated compounds, and in methods of producingisoprenoid compounds.