A multivalent immunogen composition that has 15 different polysaccharide Protein Conjugates. Each consists of a conjugated capsular polysaccharide prepared from a different Serotype of Streptococcus pneumoniae (1, 3, 4, 5, 6a, 6B, 9V, 7f, 14, 18C, 19F, 23F, 19a, 22F, or 33F) conjugated to a Carrier Protein, preferably CRM 197.The immunogen composition, preferably formulated as a vaccine adjuvant on an Aluminum base, provides broad coverage against pneumococcal disease, particularly in Infants and small children.Una composicion inmunogena multivalente que tiene 15 conjugados de polisacáridos- proteína distintos. Cada conjugado consiste en un polisacárido capsular preparado a partir de un serotipo diferente de Streptococcus pneumoniae (1, 3, 4, 5, 6A, 6B, 7F, 9V, 14, 18C, 19A, 19F, 22F, 23F o 33F) conjugado a una proteína portadora, preferentemente CRM-197. La composicion inmunogena, preferentemente formulada como una vacuna sobre un adyuvante a base de aluminio, proporciona una amplia cobertura contra la enfermedad neumococica, particularmente en infantes y ninos pequenos.
