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Toxin-derived delivery constructs for oral delivery
专利权人:
Applied Molecular Transport Inc.;Keyi Liu;Julia Mackay;Weijun Feng;Thomas Hunter
发明人:
LIU, Keyi,MACKAY, Julia Dawn,FENG, Weijun,HUNTER, Thomas Carl,MRSNY, Randall J.
申请号:
AU2019230230
公开号:
AU2019230230A1
申请日:
2019.03.08
申请国别(地区):
AU
年份:
2020
代理人:
摘要:
The present disclosure relates to isolated non-naturally occurring delivery constructs comprising a bacterial toxin-derived delivery construct coupled to a biologically active therapeutic cargo; wherein the delivery construct is capable of delivering the biologically active cargo via transcytosis transport across an epithelial cell; and wherein the delivery construct does not comprise a bacterial toxin-derived translocation domain or a bacterial toxin-derived catalytic (cytotoxic) domain.
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中国工程科技知识中心
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http://www.ckcest.cn/home/
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