Pharmacological combinations, including BCR-ABL inhibitors selected from diphenylamine derivatives and Nilotinib； pharmacological synthesis； and BCR-ABL combination therapy for positive leukemia.
THE UNIVERSITY COURT OF THE UNIVERSITY OF GLASGOW.;NOVARTIS AG
发明人:
PEUKERT STEFAN,DORSCH MARION,COPLAND MHAIRI,IRVINE DAVID,MANLEY PAUL W
申请号：
CL2012000350
公开号：
CL2012000350A1
申请日:
2012.02.10
申请国别(地区):
CL
年份:
2012
代理人:
摘要：
Pharmaceutical Combination comprising an inhibitor of Smoothened biphenyl derivative and an inhibitor of bcr abl； Pharmaceutical composition comprising these compounds and use in treatment；For BCR ABL Positive Leukemia.Combinación farmacéutica que comprende un inhibidor de smoothened derivado de bifenilo y un inhibidor de BCR-ABL； composición farmacéutica que comprende a dichos compuestos； y uso en el tratamiento de leucemia positiva para BCR-ABL.
