Korea Research Institute of Bioscience and Biotechnology
发明人:
Won Gon Kim,Hyun Ju Kim,Yu Jin Kim,Kyung Yun Cho
申请号:
US15311245
公开号:
US20170204052A1
申请日:
2015.05.14
申请国别(地区):
US
年份:
2017
代理人:
摘要:
The present invention relates to: coralmycin A and B, which are novel compounds exhibiting antimicrobial activity, an isomer thereof, a derivative thereof or a pharmaceutically acceptable salt thereof; a microorganism of the genus Corallococcus producing the same; and an antimicrobial use thereof.The coralmycin A and B have very strong antimicrobial activity against antibiotic-resistant bacteria such as MRSA, QRSA, VRE, VISA, etc.; Acinetobacter baumannii, which is a multidrug-resistant microorganism; and also against gram-positive microorganisms and gram-negative microorganisms. Therefore, the present invention can be very useful for prevention, treatment and alleviation of various microbial infections, and thus can be widely applied to the medical supply, quasi-drug, food, and feed industries.