DUNCAN, Kenneth, W.,CHESWORTH, Richard,SHAPIRO, Gideon,OLHAVA, Edward, James,PATANE, Michael, A.,MUNCHHOF, Michael John,KUNTZ, Kevin Wayne,JIN, Lei
申请号:
EP15811525
公开号:
EP3160477A4
申请日:
2015.06.25
申请国别(地区):
EP
年份:
2018
代理人:
摘要:
Described herein are compounds of Formula (I)-(XIII), pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof. Compounds of the present invention are useful for inhibiting PRMT5 activity. Methods of using the compounds for treating PRMT5-mediated disorders are also described.