The present invention relates to novel multiple specific binding proteinsVarious known multiplex specific binding protein formatsFor example, a novel multiple specific binding protein that complements the shortcomings of double specific antibody formatsOf the invariant region of the antibodyDoes not contain the CL region of the heavy chain and the CL region of the light chain.Problem to be solved: to provide a multiplex specific binding protein comprising a polypeptide in which a heavy chain variable region and / or a light chain variable region are continuously connected.Diagram本発明は新規多重特異的結合タンパク質に関し、従来公知の様々な多重特異的結合タンパク質フォーマット、例えば二重特異的抗体フォーマットなどが持つ短所を補完した新規多重特異的結合タンパク質であって、抗体の不変領域のうち、重鎖のCH1と軽鎖のCL領域を含まず、重鎖可変領域及び/又は軽鎖可変領域が連続して連結されているポリペプチドを含む多重特異的結合タンパク質を提供する。【選択図】 図1A