The object of the present invention is to provide an adsorbent for oral administration, which can: obviate sandy texture of granules- formed adsorbent for oral administration, reduce the volume administered compared to encapsulated adsorbent for oral administration, and be easy to take. The object of the present invention is solved by a tablet-formed pharmaceutical composition consisting of 65 % or more by weight of particulate substance as an active ingredient and one or more additives, characterized in that: (a) the particulate substance does not exhibit water solubility and swelling property in water, has a distortion rate of 2 % or less when subjected to a pressure of 2 MPa, and has a fracture strength of 5 MPa or more, (b) the tablet-formed pharmaceutical composition comprises one or more particle-formulating additives wherein the amount of the particle-formulating additives is 1 % or more by weight in total with respect to the weight of the tabletformed pharmaceutical composition, and a thin layer of the particle-formulating additive can be formed when 0.5 mL of solution or dispersion liquid of the particle-formulating additive of 1 % by weight is dropped on a plane surface of fluorine resin and heat-dried.
