Dharmakumar, Rohan,Li, Debiao,Tsaftaris, Sotirios A.
申请号:
AU2012250539
公开号:
AU2012250539A1
申请日:
2012.05.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
The invention provides methods for diagnosing coronary heart disease in a subject in need thereof comprising administering an admixture comprising CO2 to a subject to reach a predetermined PaCO2 in the subject to induce hyperemia, monitoring vascular reactivity in the subject and diagnosing the presence or absence of coronary heart disease in the subject, wherein decreased vascular reactivity in the subject compared to a control subject is indicative of coronary heart disease. The invention also provides methods for increasing sensitivity and specificity of BOLD MRI.