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Novel Prostate Kallikrein Allergen
专利权人:
发明人:
Lars Mattsson,Jonas Lidholm,Henrik Everberg
申请号:
US14930737
公开号:
US20160051666A1
申请日:
2015.11.03
申请国别(地区):
US
年份:
2016
代理人:
摘要:
Methods for treatment of a Type I allergy in a mammal comprise administering to an individual in need of such treatment a polypeptide of SEQ ID NO: 1 or the mature protein, amino acids 25-260, of the polypeptide of SEQ ID NO: 1, or a fragment of the polypeptide or the mature protein, which fragment shares epitopes for antibodies with the polypeptide or the mature protein, respectively, or a hypoallergenic form thereof that is modified to abrogate or attenuate its IgE binding response. Diagnostic kits comprise the polypeptide of SEQ ID NO: 1 or the mature protein, amino acids 25-260, of the polypeptide of SEQ ID NO: 1, immobilized on a solid support.
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