compound pharmaceutical composition, method for inhibiting ck1 activity, method for inhibiting ck2 activity and use of a compound or pharmaceutical composition
CARMEN M. BALDINO,CHEE SENG LEE,JUSTIN L. CASERTA,ROBERT B.NICEWONGER
申请号：
BR112012015248
公开号：
BR112012015248A2
申请日:
2010.12.23
申请国别(地区):
BR
年份:
2017
代理人:
摘要：
Disclosed are compounds, pharmaceutical compositions containing those compounds, and uses of the compounds and compositions as modulators of casein kinase 1 (e.g., CK1gamma), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFbeta pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway. Uses are also disclosed for the treatment or prevention of a range of therapeutic indications due at least in part to aberrant physiological activity of casein kinase 1 (e.g., CK1gamma), casein kinase 2 (CK2), Pim 1, Pim2, Pim3, the TGFbeta pathway, the Wnt pathway, the JAK/STAT pathway, and/or the mTOR pathway.
