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ANTICORPS OLIGOMÈRE HUMANISÉ ANTI-SUBSTANCE B-AMYLOÏDE
专利权人:
Kyowa Hakko Kirin Co.; Ltd.
发明人:
申请号:
EP10806567.3
公开号:
EP2463369A1
申请日:
2010.08.06
申请国别(地区):
EP
年份:
2012
代理人:
摘要:
An anti-cognitive dysfunction agent comprising a humanized antibody which does not bind to Aβ monomers and specifically binds only to Aβ oligomers and a fragment thereof as an active ingredient, and an therapeutic antibody which can be treat Alzheimer's disease by specifically binding amyloid β protein oligomer (Aβ oligomer) which is considered to be a cause of Alzheimer's disease are required. The present invention can provide an anti-Aβ oligomer humanized antibody and a method for treating Alzheimer's disease using the humanized antibody. An agent for treating Alzheimer's disease; an agent for suppressing formation of neuritic plaque; an inhibitor of formation of Aβ amyloid fiber; a method for at least one of preventing and treating cognitive dysfunction or Alzheimer's disease, comprising the step of administering the humanized antibody; and a method for suppressing progression of Alzheimer's disease, comprising the step of administering the humanized antibody.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/
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