You-Jin Kim,Hyun Ju In,HeeJi Lim,Sun-Dong Jang,Jung-Sik Yoo,Gyung Tae Chung
申请号：
US16708797
公开号：
US20200230227A1
申请日:
2019.12.10
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The present invention relates to a recombinant antigen derived from Zika virus E protein and use thereof. Specifically, the present invention provides a polynucleotide encoding Zika virus E protein domain III alone or repeatedly three times, a recombinant plasmid vector comprising the polynucleotide, and a DNA vaccine composition that may induce an immune response to Zika virus by expressing a Zika virus antigen protein effectively. In addition, the present invention provides a neutralizing antibody against Zika virus obtained using the polynucleotide and a method for preparing the neutralizing antibody.
