МЭЙТС Шэрон (US),ЛИ Пен (US),ТОМЕШ Джон Чарльз (US),ДЭВИС Роберт (US),УЭННОДЖЛ Лоренс П. (US),ЧЖАН Цян (US)
申请号：
RU2012149633/04
公开号：
RU2012149633A
申请日:
2011.04.22
申请国别(地区):
RU
年份:
2014
代理人:
摘要：
1. The compound of formula I: where X is —N (H) - or —N (CH) and Y is —C (H) (OH) -； X is —N (H) when Y is - ABOUT-； or X is —O— and Y is —C (H) (OH)； in free or salt form, provided that the compound is not produced in a mammal through the metabolism of a compound of formula Q: wherein X is —N (H) - or —N (CH) - and / or Y represents —C (═O)； X represents —N (CH) - and Y represents —O—； or X is —O— and Y is —C (═O) -. 2. A compound of formula I: wherein X is —N (H) - or —N (CH) and Y is —C (H) (OH) -； X is —N (H) when Y is —O— ； or X is —O— and Y is —C (H) (OH)； in solid form. 3. A compound according to claim 1 or 2, wherein said compound is in salt form. A compound according to claim 1 or 2, wherein the salt is selected from the group consisting of toluolosulfonic, fumaric and phosphoric acid addition salts. A compound according to claim 1 or 2, wherein said compound is in free or salt form. A compound according to claim 1 or 2, wherein said compound does not substantially contain a compound of formula Q: wherein X is —N (H) - or —N (CH) - and / or Y is —C (= O)； X represents —N (CH) - and Y represents —O—； or X is —O— and Y is —C (═O) -. 7. A compound according to claim 1 or 2, wherein said compound does not substantially contain a compound of formula Q: wherein Y is —C (═O) and / or X is —N (CH) -. 8. A compound of formula II-A: wherein X is —N (CH) -, —N (H) - or —O—, in free or salt form. 9. A compound of formula II-B: wherein X is —N (CH) -, —N (H) - or —O—, in free or salt form1. Соединение формулы I:где X представляет собой -N(H)- или -N(CH) и Y представляет собой -C(H)(OH)-；X представляет собой -N(H), когда Y представляет собой -О-； илиX представляет собой -O- и Y представляет собой -C(H)(OH)；в свободной или солевой форме, при условии, что соединение не вырабатывается у млекопитающего посредством метаболизма соединения формулы Q:где X представляет собой -N(H)- или -N(CH)- и/или Y представляет собой -C(=О)；X представляет собой -N(CH)- и Y представляет собой
