The invention relates to Lactobacillus plantarum capable of relieving lead toxicity and the application thereof. The Lactobacillus plantarum CCFM8661 provided by the invention has acid resistance, excellent tolerance to lead ions in vitro with capability of tolerating initial concentration of 150mg/L of lead ion solution and good lead ions binding capacity, thus can lower the lead contents in blood, livers, kidneys and stomachs of mice exposed to lead, significantly recover the antioxidant index of the mice exposed to lead, and relieve the pathological symptoms of the mice exposed to lead. The Lactobacillus plantarum CCFM8661 can be used for preparing pharmaceutical compositions and fermented foods capable of relieving lead toxicity, and has a very wide application prospect.
