FONDAZIONE ISTITUTO ITALIANO DI TECNOLOGIA;UNIVERSITA' DEGLI STUDI DI PADOVA
发明人:
DE VIVO, Marco,ORTEGA MARTINEZ, Jose Antonio,SISSI, Claudia,ARENCIBIA JIMENEZ, Jose Manuel,DE VIVO MARCO,ORTEGA MARTINEZ JOSE ANTONIO,SISSI CLAUDIA,ARENCIBIA JIMENEZ JOSE MANUEL
申请号：
IT201700028709
公开号：
IT201700028709A1
申请日:
2017.03.15
申请国别(地区):
IT
年份:
2018
代理人:
摘要：
The invention relates to a class of 5-carboxamide-2-thiobarbituric acid derivatives which inhibits human type II topoisomerase (topoII) enzyme and to use thereof as medicaments especially for blocking the proliferation of cancer cells and treating cancer. The invention also provides a method for the manufacture of the 5-carboxamide-2-thiobarbituric acid derivatives.
