A biopsy kit, comprising a penetration rod having a distal end portion, a cutting tube enclosing the penetration rod, comprising circumventing cutting means. The cutting tube is extendable from the penetration rod for cutting and enclosing a piece of target tissue, and a cutting device is extendable from the penetration rod and comprises distal cutting means for cutting off the piece of target tissue from the body. A method: penetrating tissue using a penetration rod upon reaching the tissue to be removed, carrying out the following two steps in any consecutive order: extending a cutting device from the penetration rod to penetrate the target tissue, extending a cutting tube to cut out and enclose the target tissue and additionally cutting off the piece of target tissue using a cutting means of the cutting device after extending the cutting device either before or after extending the cutting tube.