A system and method for training program generation and modification of that program based on assessed functional state and/or workload performance. User-interface logic preferably operating on a mobile device permits a user to record bio-signals indicative of functional state. Assessment-adjustment logic, that may be located at a distance, conducts body system assessments from the received bio-signal data and produces training session targets based on the current functional state of the user. User training objective data may be input through the user-interface logic. Workload performance may be monitored and the training session targets modified based on measured past performance to improve future performance. Various embodiments are disclosed.