Lewis, Andrew Lennard,Stratford, Peter William,Forster, Richard Edward John
申请号:
AU2009321621
公开号:
AU2009321621B2
申请日:
2009.11.25
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
There is provided a composition comprising microspheres which comprise a water-insoluble, water-swellable polymer and associated with the polymer, in releasable form, a chemotherapeutic agent, for use in the treatment of a pancreatic tumour or cyst, wherein the microspheres, when equilibrated in water at 37°C, comprise at least 40 wt% water based on weight of polymer plus water, wherein the polymer is anionically charged at pH7 and the chemotherapeutic agent is cationically charged and electrostatically associated with the polymer. Also provided are methods of treating pancreatic tumours or cysts using this composition.