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HUMANIZED ANTI IGE ANTIBODIES THAT CROSSLINK CD23 ON B LYMPHOCYTES BUT DO NOT SENSITIZE MAST CELLS
专利权人:
发明人:
CHEN JIUN BO,SHIUNG YU YU,CHANG TSE WEN
申请号:
IN201617033357
公开号:
IN201617033357A
申请日:
2016.09.29
申请国别(地区):
IN
年份:
2017
代理人:
摘要:
A novel humanized anti IgE antibody is disclosed. The antibody is capable of binding to free IgE membrane bound IgE on B lymphocytes IgE bound by CD23 but not to IgE bound by high affinity IgE.Fc receptor on mast cells. The present invention relates to the treatment of IgE mediated diseases including allergic asthma allergic rhinitis atopic dermatitis food allergy chronic spontaneous (idiopathic) urticaria chronic rhinosinusitis systemic mastocytosis cutaneous mastocytosis allergic bronchopulmonary aspergillosis recurrent idiopathic angioedema and eosinophil associated gastrointestinal disorder by administering the anti IgE antibody of the present invention.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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