An object of the present invention is to provide a therapeutic agent or a prophylactic agent for neuropathic pain, by which a synergistically-enhanced analgesic effect is obtained at a dose at which a calcium channel ±2´ ligand does not produce any side effects as well as which agent does not produce any new side effects on the central nervous system. The present invention provides a therapeutic agent or a prophylactic agent for neuropathic pain comprising as effective ingredients a cyclohexane derivative, represented by the following formula, or a pharmaceutically acceptable salt thereof or a prodrug thereof, and a calcium channel ±2´ ligand.
