Hariri, Robert J.,Kaplunovsky, Aleksandr M.,Murphy, Patricia A.
申请号：
AU2011201662
公开号：
AU2011201662B2
申请日:
2011.04.06
申请国别(地区):
AU
年份:
2013
代理人:
摘要：
#$%^&*AU2011201662B220130207.pdf#####Abstract The present invention relates to collagenous membranes produced from amnion, herein referred to as a collagen biofabric. The collagen biofabric of the invention has 5 the structural integrity of the native non-treated amniotic membrane, i.e., the native tertiary and quaternary structure. The present invention provides a method for preparing a collagen biofabric from a placental membrane, preferably a human placental membrane having a chorionic and amniotic membrane, by decellularizing the amniotic membrane. In a preferred embodiment, the amniotic membrane is completely decellularized. The collagen biofabric of 10 the invention has numerous utilities in the medical and surgical field including for example, blood vessel repair, construction and replacement of a blood vessel, tendon and ligament replacement, wound-dressing, surgical grafts, ophthalmic uses, sutures, and others. The benefits of the biofabric are, in part, due to its physical properties such as biomechanical strength, flexibility, suturability, and low immunogenicity, particularly when derived from 15 human placenta.
