Useful chemical compound is offered as a preventive of the disease and the like which blood plasma uric acid value abnormally originates or curative medicine.This invention has xanthin oxydase inhibition activity, the usefulness, the fused heterocycle derivative which is displayed with below-mentioned formula (i), regards that professional drag or that salt etc as a preventive of the disease which blood plasma uric acid value abnormally originates or curative medicine. In formula (i), as for T trifluoromethyl, nitro or cyano As for ring Q heteroaryl As for X and X becoming independent, CH or N As for ring U aryl or heteroaryl As for m integer 0 - 2 As for n integer 0 - 3 As for R hydroxyl group, amino or C alkyl R, is C alkyl and C alkoxy C alkyl etc.< Conversion 1 >血漿尿酸値異常に起因する疾患等の予防又は治療薬として有用な化合物を提供する。本発明は、キサンチンオキシダーゼ阻害活性を有し、血漿尿酸値異常に起因する疾患の予防又は治療薬として有用な、下記式(I)で表される縮合複素環誘導体、そのプロドラッグ、又はその塩等に関する。式(I)中、Tはトリフルオロメチル、ニトロ又はシアノ;環Qはヘテロアリール;X1及びX2は独立してCH又はN;環Uはアリール又はヘテロアリール;mは0~2の整数;nは0~3の整数;R1は水酸基、アミノ又はC1-6アルキル;R2は、C1-6アルキル、C1-6アルコキシC1-6アルキル等である。【化1】
