SUBSTITUTED 5-HYDROXYOXINDOLES AND THEIR USE AS ANALGESICS AND FEVER REDUCERS

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专利权人:

CARAFE DRUG INNOVATION; LLC

发明人:

John R. CARON,Robert B. RAFFA,Kenneth G. CARSON

申请号：

US15571169

公开号：

US20180256543A1

申请日:

2016.05.03

申请国别(地区):

US

年份:

2018

代理人:

摘要：

The present invention provides compounds and compositions which are useful in methods for modulating pain and fevers in a subject. These compounds are of the structure of formula (I), wherein Rx-R4, X, Y, and Z are defined herein, or a pharmaceutically acceptable salt, solvate, or prodrug thereof to the subject. In one embodiment, the compound is 5-hydroxy-7-methyloxindole.

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