Medical plugs for filling a void within a patient. Medical plugs may include a channel that extends from a proximal end to a distal end of the medical plug. The medical plug may include multiple channels. The channels may be disposed on the outer surface of the medical plug or may be disposed within medical plug. A medical plug delivery system may deliver the medical plug, and medical plug delivery system may include a plug holder with a lumen. Medical plug may be housed within the lumen of a plug holder and may be frictionally engaged with the lumen. When the medical plug is wetted, the medical plug may swell and close off the channel. A kit comprising a vacuum sealed flexible enclosure may be used to prevent displacement of the medical plug within the lumen during shipping and handling.
