MOLECULES RELATED hERG ION CHANNELS AND THE USE THEREOF

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专利权人:

Huayun Deng

发明人:

Huayun Deng,Ye Fang,Ann MeeJin Ferrie,Mingqian He,Weijun Niu,Haiyan Sun,Elizabeth Tran,Ying Wei

申请号：

US13519424

公开号：

US20120329865A1

申请日:

2010.12.16

申请国别(地区):

US

年份:

2012

代理人:

摘要：

Disclosed are compounds having structural formula (I, II) or a pharmaceutically acceptable sale, solvate, clathrate, or prodrug thereof, wherein R1, R2, R3, R6, R5, and R4 are defined herein. These compounds can be useful as therapeutic agents for modulating hERG ion channels, and for improving prevention and treatment of hERG associated cardiac repolarization disorders.

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中国工程科技知识中心

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