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Nitric oxide-releasing polymers
专利权人:
Blaine G. Doletski;Robert E. Raulli;Ernst V. Arnold
发明人:
Ernst V. Arnold,Blaine G. Doletski,Robert E. Raulli
申请号:
US12940208
公开号:
US08894985B2
申请日:
2010.11.05
申请国别(地区):
US
年份:
2014
代理人:
摘要:
This invention relates to compositions comprising carbon-based diazeniumdiolates attached to hydrophobic polymers that releases nitric oxide (NO). The carbon-based diazeniumdiolated polymers release NO spontaneously under physiological conditions without subsequence nitrosamine formation. The present invention also relates to methods of preparing the carbon-based diazeniumdiolated polymers, compositions comprising such polymers, methods of using such compositions, and devices employing such polymer compositions.
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