International Business Machines Corporation;Institute of Bioengineering and Nanotechnology, Biomedical Sciences Institute
发明人:
Dylan Boday,Willy Chin,Mareva B. Fevre,Jeannette Garcia,James L. Hedrick,Eunice Leong,Nathaniel H. Park,Rudy J. Wojtecki,Yi Yan Yang
申请号：
US16451489
公开号：
US20190307684A1
申请日:
2019.06.25
申请国别(地区):
US
年份:
2019
代理人:
摘要：
The subject matter of this invention relates to block copolymers (BCPs) and, more particularly, to block copolymers capable of self-assembly into nanoparticles for the delivery of hydrophobic cargos. The BCPs include a hydrophobic block that contains a thioether functional group that is susceptible to oxidation, transforming the solubility of the block from hydrophobic to hydrophilic, thereby releasing the hydrophobic cargo of the nanoparticle.
