ZHANG, XIAOKUI,DJURETIC, IVANA,KANG, LIN,VOSKINARIAN-BERSE, VANESSA,STOUT, BHAVANI,HARIRI, ROBERT J.,HOFGARTNER, WOLFGANG,EDINGER, JAMES,LAW, ERIC,JANKOVIC, VLADIMIR
申请号：
CA3002066
公开号：
CA3002066A1
申请日:
2016.10.14
申请国别(地区):
CA
年份:
2017
代理人:
摘要：
Provided herein are methods of producing natural killer (NK) cells and/or ILC3 cells using a three-stage expansion and differentiation method with media comprising stem cell mobilizing factors. Also provided herein are methods of suppressing tumor cell proliferation using the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein, as well as methods of treating individuals having cancer or a viral infection, comprising administering the NK cells and/or ILC3 cells and the NK cell and/or ILC3 cell populations produced by the three-stage methods described herein to an individual having the cancer or viral infection.
