СУ Чжуан (US),ЛОНГ Чжэнюй (US),ХУАН Чжэньнянь (US),ЯН Суйчжоу (US)
申请号：
RU2013130256/15
公开号：
RU2013130256A
申请日:
2011.12.05
申请国别(地区):
RU
年份:
2015
代理人:
摘要：
1. The compound of formula (I): or a pharmaceutically acceptable salt thereof, wherein: R is n-butyl, (E) -but-2-enyl or； R is ethyl, 1-hydroxyethyl, isopropyl or n-propyl； W is O, S or NR； R is hydrogen； (CC) alkyl optionally substituted by one or more R groups which may be the same or different； (CC) alkenyl or (CC) alkynyl； (CC) cycloalkyl which is optionally substituted by (CC) alkyl； phenyl optionally substituted with one to five groups, which may be the same or different, selected from halogen, -O (C- C) alkyl, -C (= O) O (CC) alkyl, amino, alkylamino and dialkylamino； or a heterocyclic ring, which may be saturated or unsaturated, containing five or six atoms in the ring, and from one to three heteroatoms, which be the same or different, selected from nitrogen, sulfur and oxygen； or R and R, together with the nitrogen atom to which they are attached, form a saturated or unsaturated heterocyclic ring containing from three to seven atoms in the ring, and this ring may optionally contain another heteroatom selected from groups s, consisting of nitrogen, oxygen and sulfur, and may optionally be substituted with one to four groups, which may be the same or different, selected from the group consisting of (CC) alkyl, phenyl and benzyl； R is: H； (CC) alkyl optionally substituted by one or more groups R, which may be the same or different； (CC) alkenyl, optionally substituted by one or more groups, which may be the same or different, selected from halogen, hydroxy, amino, monoalkylamino and dialkylamino； (CC) alkynyl n1. Соединение формулы (I):или его фармацевтически приемлемая соль, где:Rявляется н-бутилом, (E)-бут-2-енилом или；Rявляется этилом, 1-гидроксиэтилом, изопропилом или н-пропилом；W является O, S или NR；Rявляется водородом；(C-C)алкилом, необязательно замещенным одной или несколькими группами R, которые могут быть одинаковыми или различными；(C-C)алкенилом или (C-C)алкинилом；(C-C)циклоалкилом, который необязательно замещен (C-C)алкилом；фенилом, необязательно з
