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LOCAL COMPOSITIONS FOR THE STORAGE OR RESTORATION OF THE INTEGRITY OF THE Mucous membranes
专利权人:
РИЧЕРФАРМА С.Р.Л. (IT)
发明人:
ДИ СКЬЕНА Микеле Джузеппе (IT)
申请号:
RU2013125021/15
公开号:
RU2013125021A
申请日:
2011.11.29
申请国别(地区):
RU
年份:
2014
代理人:
摘要:
1. A topical composition comprising choline alfoscerate and hyaluronic acid or its pharmaceutically acceptable salts, and at least one pharmaceutically acceptable excipient or carrier, for use to maintain and restore the integrity of the mucous membranes. The local composition according to claim 1, where the concentration of choline alfoscerate is in the range from 0.001% wt./about. up to 99% w / v. 3. The local composition according to claim 2, where the concentration of choline alfoscerate is in the range from 0.010% wt./about. up to 50% w / v. 4. A topical composition according to claim 1, wherein the hyaluronic acid is in the form of a sodium salt. The local composition according to claim 1, where the molecular weight of hyaluronic acid or its pharmaceutically acceptable salt is from 800,000 to 4,000,000 Da. The local composition according to claim 4, where the molecular weight of hyaluronic acid or its pharmaceutically acceptable salt is from 800,000 to 4,000,000 Da. A local composition according to claim 1, containing at least one additional active ingredient selected from the group consisting of mesalazine, licorice and its derivatives, silver and its derivatives, aloe vera, allantoin and its derivatives, chlorhexidine and benzalkonium chloride. The local composition according to claim 7, where the active component is mesalazine. Local composition according to claims 1-8 in the form of an aqueous gel. 10. Local composition according to claims 1-8 for use in humans and in veterinary medicine. 11. The local composition according to claim 9 for use in humans and in veterinary medicine. A topical composition according to claims 1-8 for use in the prevention and treatment of inflammatory disorders and / or damage to the oral mucosa. 13. The topical composition according to claim 9 for use in the prevention and treatment of1. Местная композиция, содержащая холин альфосцерат и гиалуроновую кислоту или ее фармацевтически приемлемые соли, и по меньшей мере один фармац
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中国工程科技知识中心
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