Fully or partially deuterated Analogue compounds 4 - (3 - metanosulfonil - phenyl) - 1 - propyl piperidine (pridopidine)； Pharmaceutical composition that comprises； method of treatment, prevention or Relief of a disorder mediated by dopamine.
The present invention provides novel deuterated analogs of Pridopidine, i.e. 4-(3-methanesulfonyl-phenyl)-1-propyl-piperidine. Pridopidine is a drug substance currently in clinical development for the treatment of Huntington's disease. In other aspects the invention relates to pharmaceutical compositions comprising a deuterated analog of Pridopidine of the invention, and to therapeutic applications of these analogs.<；p>；LA PRESENTE INVENCIÓ；N SE REFIERE A UNA COMPOSICIÓ；N TARMACÉ；UTICA QUE COMPRENDE UN COMPUESTO REPRESENTADO POR LA FÓ；RMULA 1, O UNA SAL FARMACÉ；UTICAMERDE ACEPTABLE DEL MISMO； COMPOSICIÓ；N FARMACÉ；U)ICA QUE COMPRENDE DICHA COMPOSICIÓ；N JUNTO A UN VEHICULO FARMACÉ；UTTCAMENTE ACEPTABLE； Y SU USO PARA EL TRATAMIENTO, PREVENCIÓ；N O ALIVIO DE UN TRASTORNO MEDIADO POR DOPAMINA.<；/p>；
