The present invention relates to an ophthalmic aqueous composition containing PGF2α analogues for treating ocular hypertension and glaucoma, to a method for treating ocular hypertension and glaucoma by administering said composition to a subject in need of such treatment, and to a method for increasing aqueous solubility and stability of PGF2α analogues in an aqueous composition.本發明係關於用於治療高眼壓及青光眼之含有PGF2α類似物之眼用水性組成物,藉由將所述組成物向需要此治療之目標給藥而治療高眼壓及青光眼之方法,以及用於增加水性組成物中PGF2α類似物之水溶性及安定性之方法。