Antimicrobial compositions are provided that include a hydroalcoholic solvent system comprising a lower C2-C5 alcohol and water a cationic antimicrobial agent such as chlorhexidine gluconate a fatty component containing at least one free hydroxyl group, such as a C12-C2I fatty alcohol, a C12-C21 fatty ester, a C12-C21 fatty ether, a C12-C2I fatty amide, and combinations thereof and optionally an emollient ester such as diesters of bibasic acids and trimesters of citric acid. The compositions described herein display improved antimicrobial efficacy and improved cosmetic elegance.Linvention concerne des compositions antimicrobiennes contenant un système de solvants hydroalcooliques comprenant un alcool C2-C5 et de leau un agent antimicrobien cationique, tel que du gluconate de chlorhexidine un composant gras contenant au moins un groupe hydroxyle libre, tel quun alcool gras C12-C21, un ester gras C12-C21, un éther gras C12-C21, un amide gras C12-C21, et des combinaisons de ceux-ci et éventuellement un ester émollient, tel que des diesters dacides dibasiques et des triesters dacide citrique. Les compositions décrites ont un effet antimicrobien amélioré et un aspect cosmétique amélioré.