Auwerx, Johan,Lagouge, Marie,Argmann, Carmen,Milne, Jill,Dipp, Michelle,Milburn, Michael
申请号:
AU2006269459
公开号:
AU2006269459B2
申请日:
2006.07.07
申请国别(地区):
AU
年份:
2013
代理人:
摘要:
Provided herein are methods and compositions for treating or preventing metabolicdisorders, such as obesity and diabetes. Methods may comprise modulating theactivity or level of a sirtuin, such as SIRTl or Sir2. Exemplary methods comprisecontacting a cell with a sirtuin activating compound, such as a flavone, stilbene,flavanone, isoflavone, catechin, chalcone, tannin or anthocyanidin, or aninhibitory compound, such as nicotinamide.