An anti-pyretic herbal composition comprises Godanti bhasm 23 % w/w, Maha Sudershan churna 18% w/w, Purified Alum 9% w/w, Picrorhiza kurroa 9% w/w, Tinospora cordifolia 9% w/w, Andrographis paniculata 9% w/w, Zingiber officinale 5% w/w, Piper nigrum 5% w/w, Piper longum 5% w/w, Purified Dhatura Metal 3% w/w, Purified Aconitum Ferox Wall 1% w/w, Purified Sulphur 1% w/w, Parad bhasm 1% w/w, 10% w/w Ocimum sanctum, and 25% w/w Citrus aurantifolia, wherein, the Maha Sudershan churna, Picrorhiza kurroa, Tinospora cordifolia, Andrographis paniculata are used in dry extract form whereas, Ocimum sanctum, Citrus aurantifolia and Zingiber officinale are used in the form of the juices of herbs dried into powder and the composition reduces the activity of hypothalamus, speeds up the heat radiation of the body resulting in sweating the composition targets microorganisms preferably malarial parasites, salmonella, typhus , virus and cures ingestion caused by toxins.