This utility model discloses a formulation of an antibacterial and antifungal cream for treating skin infections caused b yStaphylococcus aureus and Aspergillus niger pathogenic microorganisms using Ageratum cnyzoides ethanolic crude extracts as active ingredient. The cream composed of 16.5 pcnt by weight oil phase, 83 pcnt by weight water phase of the active ingredients, and 0.5 pcnt preservative.