CHUGAL SEIYAKU KABUSHIKI KAISHA;AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH
发明人:
FINK, KATJA,WANG, CHENG-I,NG, LISA FONG POH,RENIA, LAURENT,SAMPEI, ZENJIRO,KOO, XING'ER CHRISTINE
申请号：
CA3093729
公开号：
CA3093729A1
申请日:
2019.03.15
申请国别(地区):
CA
年份:
2019
代理人:
摘要：
The disclosure provides anti-dengue virus (anti-DENV) antibodies having a cross-reactivity to Zika virus (ZIKV) and methods of making and using the same. The anti-DENV antibodies have uses that include treating or preventing ZIKV infection. In addition, claimed antibodies may further comprise variant Fc regions containing LALA, KAES & ACT5 mutations.
