METHODS AND COMPOSITIONS FOR THE TREATMENT OF INSULIN-ASSOCIATED MEDICAL CONDITIONS

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专利权人:

Eran Hornstein

发明人:

Eran Hornstein,Tal Melkman-Zehavi,Roni Oren

申请号：

US13879843

公开号：

US20130209440A1

申请日:

2011.10.10

申请国别(地区):

US

年份:

2013

代理人:

摘要：

A method of increasing insulin content in a pancreatic beta cell is disclosed. The method comprising expressing in the pancreatic beta cell an exogenous polynucleotide encoding at least one microRNA or a precursor thereof, wherein the microRNA is selected from the group consisting of miR-15, miR-16, miR-24, miR-26, miR-27, miR-29, miR-30, miR-129, miR-141, miR-148, miR-182, miR-200, miR-376 and Let-7, thereby increasing the insulin content in the pancreatic beta cell.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/