Combination therapies using anti-Pseudomonas Psl and PcrV binding molecules

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专利权人:

MedImmune Limited; LLC;MedImmune, LLC;MedImmune

发明人:

Digiandomenico, Antonio,Warrener, Paul,Stover, Charles,Sellman, Bret,Minter, Ralph,Guillard, Sandrine,Rust, Steven,Tomich, Mladen,Venkatraman, Vignesh,Varkey, Reena,Peng, Li,Damschroder, Melissa,Chowd

申请号：

AU2013341349

公开号：

AU2013341349A8

申请日:

2013.11.06

申请国别(地区):

AU

年份:

2015

代理人:

摘要：

Using anti-Pseudomonas PsI and PcrV binding molecules and related compositions in prevention and treatment of Pseudomonas infection are disclosed. Further provided are isolated binding molecules which specifically bind to Pseudomonas PcrV or Pseudomonas PsI, and bispecific antibodies that specifically bind to Pseudomonas PcrV and Pseudomonas PsI. The sequences of heavy chain and light chain as well as sequences of complementarity determining regions (CDRs) of these binding molecules are further disclosed.

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中国工程科技知识中心

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http://www.ckcest.cn/home/